The Niger Delta region of Nigeria, despite its abundant natural resources, continues to experience underdeveloped manufacturing performance, constrained by inadequate infrastructure, unreliable energy supply, and limited technological adoption. This study examined the impact of trade, tariffs, renewable energy adoption, and information and communication technology (ICT) on manufacturing sector outcomes in the region. Using secondary data from the Manufacturers Association of Nigeria, National Bureau of Statistics, and World Bank Enterprise Surveys, an ex-post facto research design was employed. Econometric analysis was conducted through the Augmented Dickey-Fuller unit root test, Johansen co-integration test, and Vector Error Correction Model (VECM) to examine bothshort- and long-run relationships among the variables. Findings reveal a statistically significant long-run relationship between manufacturing output and its determinants. Tariffs exhibited a negative and significant short-run effect, reflecting higher production costs from imported inputs, while renewable energy adoption positively influenced output, highlighting the benefits of stable and sustainable energy sources. ICT adoption showed marginal short-run effects but is expected to enhance long-term productivity. The study concludes that trade openness, technological advancement, and renewable energy adoption are critical for revitalizing the manufacturing sector, but their effectiveness is contingent on supportive infrastructure, institutional quality, and policy coherence. Policy recommendations include revising tariff structures to protect local industries, expanding renewable energy infrastructure, promoting technological innovation, and strengthening human capital development. Implementing these measures can position the Niger Delta as a competitive, technology-driven manufacturing hub, contributing to Nigeria’s economic diversification and sustainable industrial growth.

Keywords: Manufacturing output, Trade Policy, Technology Adoption, Renewable Energy, Niger Delta